Friday, June 28, 2019

Phosphorous Binders and the Dialysis Diet:

Hyperphosphatemia is associated with higher mortality in patients on dialysis; the choice between calcium-containing and non-calcium-containing phosphate binders continues to be debated. An observational study of over 4000 older incident dialysis patients found that the risk of fatal or nonfatal cardiovascular events or all-cause mortality was not different among patients treated with either calcium acetate or sevelamer

Phosphate Binders helps to maintain the level of the phosphate They get bind with the phosphate present in the food and removed them in the form of stool. These phosphate binders are taken within 5-10 minutes before or after the food.

people on dialysis get monthly lab results that show if their phosphorus level is in a healthy range (3.0 to 5.5 mg/dL, or as close to the laboratory reference range as possible). If your phosphorus levels aren't in a very healthy vary, you can talk with your doctor or dietitian and take action to change what you are eating. They may also adjust your phosphorus binder prescription, if you need another brand or should be taking a different amount.

Phosphorus binders work in one of two ways. Some phosphate binders, such as Renvela, work as a sponge and soak up the phosphates in the food so that it doesn’t get into the blood. Instead, it's carried through the alimentary tract and eliminated within the stool. Other phosphorus binders, like Fosrenol, Phoslo and Tums, work like a magnet. The phosphorus within the food connects to the phosphorus binder and it's carried through the alimentary tract to be eliminated.
Some folks could also be prescribed a mixture of phosphorus binders to assist keep their phosphorus level in a very healthy vary.

Friday, June 21, 2019

Discovery of urinary organ cancer driver could lead on to new treatment strategy:

Discovery of urinary organ cancer driver could lead on to new treatment strategy:

More  than ninety % of the foremost common kind of urinary organ cancer have a genetic amendment that ends up in the loss of a crucial neoplasm gene referred to as VHL. in an exceedingly study printed within the journal Science, researchers knew a brand new downstream impact of this  amendment that's serving to drive urinary organ cancer: They found that a macromolecule referred to as ZHX2 over-accumulates in these cells and helps to show on different signals concerned in cancerous growth. Their findings recommend that ZHX2 could be a potential new therapeutic target for clear cell excretory organ cell cancer, that is that the commonest kind of urinary organ cancer.

When VHL is lost the cell it accumulates a heap of proteins that triggers the signal for the cancerous the urinary organ. generally, the mutation in genes causes loss of VHL macromolecule operates. after they are gone this cell accumulates macromolecule causes stimulation in vessel block cell signals concerned in abnormal blood vessel production -- that could be a downstream impact of VHL loss -- that is a part of the quality of look after clear cell excretory organ cell cancer. Patients will show very little response to that medicine or will develop resistance

The researchers created a screening technique to get new molecules that may facilitate drive cancer once VHL is lost. This junction rectifier them to see that urinary organ cancer cells lacking VHL sometimes had a lot of ZHX2. By eliminating ZHX2 from their laboratory models, they strangled neoplastic cell growth, invasion and therefore cancer unfold. additionally, they saw that it had been committed signals that may facilitate cancer cells grow.

Friday, June 14, 2019

Advances in Nanotechnology can pave a pathway to Artificial Kidney

A surgically implantable, urinary organ|hemodialyzer|dialyzer|dialysis machine} may well be a promising various to kidney transplantation or qualitative analysis for folks with finish stage nephritic unwellness (ESRD). Around 20 million people are suffering from renal disease failure due to which they depend either depend upon dialysis or kidney transplantation. But this problem can be solved with the new development in nanotechnology.

One part of the new dialysis machine could be an atomic number 14 nano-filter to get rid of toxins, salts, some small molecules, and water from the blood. Roy's analysis team designed it supported producing strategies employed in the assembly of semiconductor physics and small mechanical device systems. The new silicon nano filters offer several advantages including more uniform pore size over dialysis filter. Nano filter is meant to perform on pressure level alone and while not a pump or electric power.

In distinction, a wearable device would allow patients to be mobile and untethered. A wearable device might conjointly offer further treatment edges from longer sessions or a lot of frequent days of chemical analysis.  The usual diet for patients on normal dialysis is extremely restricted. In distinction, on the Wearable Artificial Kidney, the patients' blood electrolytes - like sodium and potassium and their blood fluid volume remained balanced during the test, even without any diet restrictions. Regulating the amount and composition of body fluids is another job of traditional kidneys.

During the trial, the participants tolerated the treatment well and did not have any serious, adverse effects. The circulatory system, which keeps blood moving throughout the body, stayed stable in all the patients. however, it also has some technical problems which can be overcome with time.

Thursday, April 18, 2019

Nephrologists Congress 2019

About Conference

  Nephrology Conferences regards each one of the individuals to go to the "Nephrologists Congress 2019" amidst November 11-12, 2019 at Istanbul, Turkey which melds brief keynote presentations, speaker talks, Exhibition, Symposia, and Workshops. Nephrologists Congress 2019 has been designed to extensively explore a variety of scientific and clinical aspects of hypertension & Kidney disease throughout the lifespan, and throughout the spectrum of kidney disease.
Nephrologists Congress 2019 will be an international event focusing on the core knowledge and major advances in the ever-expanding field of Nephrology & Hypertension by attracting experts on a global scale. This year, we also hope to bring together experiences from different countries and exchange their views, reinforce knowledge base, and learn new concepts.
With the participation of outstanding international experts, we hope productive discussions would stimulate new creative ideas to translate new discoveries into better diagnosis and treatment of Renal Diseases. We sincerely invite you to join us in this very informative annual conference and collaborate in the global action in reducing the burden of Hypertension & Renal Diseases. Your presence will certainly add value to the conference and very much appreciated!
2019 Highlights:
  • 100+ Participation (60 Industry: 40 Academia)
  • 5+ Keynote Speakers
  • 30+ Plenary Speakers
  • 5+ Exhibitors
  • 19 Innovative Educational Sessions
  • 5+ Workshops
  • B2B Meetings
Why to attend???
With members from around the world focused on learning about nephrology and its advances; this is your best opportunity to reach the largest assemblage of participants from the nephrology community. Conduct presentations, distribute information, meet with current and potential scientists, make a splash with new drug developments, and receive name recognition at this 2-day event. World-renowned speakers, the most recent techniques, developments, and the newest updates in nephrology are hallmarks of this conference.
Target Audience:
  • Nephrologists
  • Nephrology Scientists
  • Heads, Deans and Professors of Nephrology & Cardiology departments
  • Scientists and Researchers organizers
  • Doctors
  • Medical Colleges
  • Writers
  • Healthcare professionals
  • Founders and Employees of the related companies
  • Clinical investigators
  • Hospitals and Health Services
  • Pharmaceutical companies
  • Laboratory members
  • Training institutions
  • Support organizers
  • Data Management Companies
  • Nephrologists training and education
  • Nurse and nursing education institutions

Conference Highlights

Special Issues

  •  All accepted abstracts will be published in respective Supporting International Journals.
  •  Abstracts will be provided with Digital Object Identifier by Cross Ref.

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